The field of primary immunodeficiencies (PID) was just revving up when I entered it in the eighties. This branch of medical sciences has gone through intense development over the past decades by creating new concepts and providing explanation for the molecular genetic basis of more than 450 inborn errors of immunity (Tangye et al, JoCI, 2021). We have learned that infections result from specific human germline genetic variability which paved the way of the genetic theory of infectious diseases. However, the new knowledge was not rapidly and evenly spread in the medical community. I still recall the shocking data from the European Society for Immunodeficiencies (ESID) registry presented by Lennart Hammarström in Debrecen, August 2002, and showing that the number of registered PID patients was less than 10 in many countries of Eastern and Central Europe (ECE).
Thus, the J Project physician education and clinical research collaboration program was to improve diagnosis and care of PID patients in ECE. The J Project has spread and reached milestone successes in terms of the number of diagnosed and treated patients and at a later stage, establishing genetic centers for mutational analysis in Debrecen, Hungary and various ECE countries and organizing the J Daughters Project network in 2009. These successes could only be achieved with the outstanding ambition and remarkable contribution by leaders of the colleagues from ECE, as well as from leaders of the J Daughters projects in Siberia and Far East Russia, Central Asia, Turkey, Iran, and Egypt. The Project has been generously supported by the Jeffrey Modell Foundation, and several pharmaceutical companies provided educational grants. All activities are coordinated and supported by the Foundation for Children with Immunodeficiencies since 2014. I am grateful to all our sponsors and judge myself fortunate to have caught the primary immunodeficiency wave in the past decades.
November 14, 2020
Asghar Aghamohammadi (born in Ahvaz, Khuzestan province, Iran) was an Iranian medical scientist, immunologist and clinical immunology professor at the Tehran University of Medical Sciences. He has studied in many institutes, including the Ahvaz Jundishapur University of Medical Sciences, Tehran University of Medical Sciences, Great Ormond Street Hospital (Institute of Child Health) and the University of Toyama. He has been one of the most distinguished Iranian Immunologists and awarded many national scientific prizes for his works, mostly in the field of primary immunodeficiency. He was recognized internationally by hundreds of publications in this field and was the most important contributor to awareness of primary immunodeficiencies and to the management of immunodeficient patients in Iran. Read more…
November 14, 2020
Respecting the USERN slogan of “Science without Borders” and in order to eliminate the geographical border of science, the USERN Congress and Prize Awarding Festival is to be held annually hosted by a scientific center worldwide. Proudly, to date, we have organized the annual USERN Congresses and Festival in Iran (Tehran) USERN 2016, Ukraine (Kharkiv) USERN 2017, and Italy (Reggio Calabria) USERN 2018, Hungary (Budapest) USERN 2019, respectively; all highly welcomed by the international academic population.
Coming up next, the 5th USERN Congress and Prize Awarding Festival will be held on November 7-10, 2020 in the beautiful city of Tehran, Iran, in a hybrid model (attend “in-person” event with a “virtual” online component), which is also supported by J Project.
Now, in order to appreciate the J Project Activities, we would like to extend an invitation to all J Project Members. They are more than welcome to join us in USERN 2020 congress, virtually for FREE! Should they be interested, please use the link below to sign up:
November 14, 2020
President elect: Fabio Candotti
Secretary: Eleonora Gambineri
Treasurer: Stefano Volpi
Inborn Error Working Party: Michael Albert
Clinical Working Party: Siobahn Burns
This website reconstruction was supported by the Jeffrey Modell Foundation and the European Society for Immunodeficiencies